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India Has Skill, Technology, Manpower That 'New' Kuwait Needs: PM ModiLuigi Nicholas Mangione, the suspect in the fatal shooting of a healthcare executive in New York City, apparently was living a charmed life: the grandson of a wealthy real estate developer, valedictorian of his elite Baltimore prep school and with degrees from one of the nation's top private universities. Friends at an exclusive co-living space at the edge of touristy Waikiki in Hawaii where the 26-year-old Mangione once lived widely considered him a “great guy,” and pictures on his social media accounts show a fit, smiling, handsome young man on beaches and at parties. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Success! An email has been sent to with a link to confirm list signup. Error! There was an error processing your request. Get the latest need-to-know information delivered to your inbox as it happens. Our flagship newsletter. Get our front page stories each morning as well as the latest updates each afternoon during the week + more in-depth weekend editions on Saturdays & Sundays.
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From wealth and success to murder suspect, the life of Luigi Mangione took a hard turnFor the past 14 years, Alex Vynokur, the co-founder of Betashares, has quietly built his company into one of the largest local providers of exchange-traded funds and one of the country’s fastest growing asset managers. In 2024, Betashares attracted inflows of $16 billion, lifting its total funds under management to $46 billion. “The focus for the past decade has very much been about building out the core ETF capability,” explains Vynokur. “We are now a steward of significant capital on behalf of more than 1 million Australian investors and over two-thirds of financial advisors.” Betashares now accounts for one-third of every dollar that goes into the Australian ETF industry, according to Vynokur, and is eyeing growth in Asia. Alex Vynokur, the chief executive of Betashares. Credit: Louie Douvis An ETF is a basket of securities that are pooled into one fund, which is traded on a stock exchange. An investor in an ETF doesn’t own the securities, instead owning units in the ETF, while the ETF provider owns the shares or assets. ETFs have grown in popularity with investors because they are cost-effective and offer exposure to thousands of diversified assets, such as a group of defence stocks, or the ASX200 index, or a variety of bonds. Globally, ETFs have had a banner year with more than $1 trillion invested into the sector, which is now worth an estimated $14 trillion. Vynokur and his family arrived in Australia from Ukraine more than three decades ago, at the time when ETFs launched. He was a teenager, and his family came with just a few hundred dollars in their pockets. Vynokur became a lawyer, then moved into venture capital, before co-founding Betashares with David Nathanson, also a former lawyer and investment banker, who had worked at Goldman Sachs and Macquarie. We’re definitely, very cautiously, studying opportunities outside of Australia. Alex Vynokur, Betashares co-founder As with any start-up, Vynokur and Nathanson put in enormous hours to build the company to where it is today, as Australia’s second-largest ETF provider behind market leader Vanguard. Both are now multi-millionaires, though there has been a physical cost, says 46-year-old Vynokur: “I didn’t have any grey hair 14 years ago.” The pay-off for both as come in the past few years. In 2021, private equity group TA Associates became Betashares’ majority shareholder, with at least 53.5 per cent ownership. In the middle of this year, Singapore’s Temasek, one of the world’s largest sovereign wealth funds, bought a minority stake. Temasek paid $300 million for that shareholding, the size of which was undisclosed. The deal ascribed a multi-billion-dollar valuation to Betashares. It was Temasek’s first investment in a financial services business in Australia. In a global portfolio valued at $S389 billion ($459 billion), Temasek has just over half invested in private assets. “They have invested with the objective of maybe having more ownership,” says Vynokur. “We’re building this business for the long term, and they are genuinely interested in long-term value creation. We’ve never been about building something up quickly and flogging it. It doesn’t mean I’m opposed to being listed one day, but we’re definitely not in a hurry to go down that path.” The proceeds are expected to help fund Betashares’ growth into new products. In the past year, the company launched retail investment platform Betashares Direct and bought a superannuation business from Bendigo and Adelaide Bank. Vynokur also believes that Betashares has more room to expand its main ETF business. Loading “According to the ASX data, there are 8 million Australians who invest outside their superannuation,” he says. “Also, if you think about younger Australians, who are locked out of the property ownership game, you know being smart with money outside of property is absolutely crucial. We have a real role to play in that.” There is also the opportunity for Betashares to expand its ETF business into Asia but, as for a priority, Vynokur won’t nominate a country. “We’re definitely, very cautiously, studying opportunities outside of Australia ... and that’s going to form part of our longer-term growth.” The Business Briefing newsletter delivers major stories, exclusive coverage and expert opinion. Sign up to get it every weekday morning . Save Log in , register or subscribe to save articles for later. License this article Investing ETFs Anne Hyland is an award-winning writer and a senior correspondent for The Sydney Morning Herald and The Age. She was previously deputy editor of Good Weekend and has worked for The AFR and as a foreign correspondent. Connect via Twitter or email . Most Viewed in Business Loading
Charleston County Government recently announced the selection of Justin Pierce as its next director of Emergency Management (full bio and headshot attached). He assumed his role on Dec. 2. Justin has over 20 years of experience in the homeland security and emergency management field and most recently served as Director of Emergency Management for Los Angeles World Airports. In that role, he served Van Nuys General Aviation Airport and LAX, which was named among the world’s top 10 busiest airports in 2023. As Director of Emergency Management, Justin helped guide the airport’s response to and recovery from COVID-19, led the planning effort for the Super Bowl LVI team arrivals, revamped LAX terminal evacuation and repopulation procedures, modernized its alert and warning capabilities, and initiated a $70 million renovation of its Emergency Operations Center. From 2016 to 2019, Justin served as Deputy Chief of the Preparedness Division for the District of Columbia’s Homeland Security and Emergency Management Agency, where he led numerous planning efforts and EOC activations in response to emergencies, National Special Security Events, and other planned events including Presidential Inaugurations, State of the Union Addresses and a Papal Visit. Additionally, he has deployed to numerous Presidentially declared disasters under the Robert T. Stafford Act. Justin received a Bachelor of Science degree from Virginia Tech University and has completed higher education programs at Georgetown University and Massachusetts Institute of Technology. In July 2024, he graduated from the Naval Postgraduate School Executive Leaders Program 2302.1. Justin is married to his wife, Marissa, and is the father of two daughters, Kennedy and Madison. "Charleston County is proud to welcome Justin Pierce as its new director of Emergency Management. His years of decisive leadership, experience navigating complex emergency scenarios, and proven ability to foster cross-sector collaboration make him the ideal candidate for this critical role. As our community continues to face evolving challenges, we are confident that Justin will enhance our preparedness and resilience, ensuring the safety and security of all who call Charleston County home," said Herbert R. Sass, III, Charleston County Council Chairman.JOHANNESBURG South Africa on Monday reiterated its call for an immediate cease-fire in Palestine and Lebanon and the initiation of a political process to secure a just and lasting peace. "South Africa once again calls on the State of Israel to realize that the only way to achieve peace is a two-state solution where Israel will be able to exist side-by-side in peace with a viable and fully independent Palestinian State within internationally recognized parameters," said a statement marking the 47th United Nations International Day of Solidarity with the Palestinian People. Pretoria highlighted that the unresolved Palestinian issue, now spanning 75 years, remains central to tensions in the Middle East. "This occasion (International Day of Solidarity) provides us with a crucial opportunity to reflect and take stock of the plight of the people of Palestine," the statement said. South Africa reaffirmed its unwavering commitment to strengthening its bond of solidarity, friendship and cooperation with Palestine. "In keeping with South Africa’s long-term and principled support for the Palestinian people, the Government of South Africa remains committed to supporting initiatives aimed at refocusing the international agenda on Palestine and a revived Middle East peace process," the statement added. The government also urged the international community to intensify efforts to assist Palestinians in achieving their aspirations for freedom, justice and the establishment of an independent state.
Autodesk Inc. stock underperforms Monday when compared to competitorsAston Villa march on in Champions League after beating RB LeipzigJOHANNESBURG South Africa on Monday reiterated its call for an immediate cease-fire in Palestine and Lebanon and the initiation of a political process to secure a just and lasting peace. "South Africa once again calls on the State of Israel to realize that the only way to achieve peace is a two-state solution where Israel will be able to exist side-by-side in peace with a viable and fully independent Palestinian State within internationally recognized parameters," said a statement marking the 47th United Nations International Day of Solidarity with the Palestinian People. Pretoria highlighted that the unresolved Palestinian issue, now spanning 75 years, remains central to tensions in the Middle East. "This occasion (International Day of Solidarity) provides us with a crucial opportunity to reflect and take stock of the plight of the people of Palestine," the statement said. South Africa reaffirmed its unwavering commitment to strengthening its bond of solidarity, friendship and cooperation with Palestine. "In keeping with South Africa’s long-term and principled support for the Palestinian people, the Government of South Africa remains committed to supporting initiatives aimed at refocusing the international agenda on Palestine and a revived Middle East peace process," the statement added. The government also urged the international community to intensify efforts to assist Palestinians in achieving their aspirations for freedom, justice and the establishment of an independent state.
For ‘A Complete Unknown,’ Arianne Phillips Had to Dress Over 4,000 People in Period CostumesNone
Luigi Nicholas Mangione, the suspect in the fatal shooting of a healthcare executive in New York City, apparently was living a charmed life: the grandson of a wealthy real estate developer, valedictorian of his elite Baltimore prep school and with degrees from one of the nation's top private universities. Friends at an exclusive co-living space at the edge of touristy Waikiki in Hawaii where the 26-year-old Mangione once lived widely considered him a “great guy,” and pictures on his social media accounts show a fit, smiling, handsome young man on beaches and at parties. Now, investigators in New York and Pennsylvania are working to piece together why Mangione may have diverged from this path to make the violent and radical decision to gun down UnitedHealthcare CEO Brian Thompson in a brazen attack on a Manhattan street. The killing sparked widespread discussions about corporate greed, unfairness in the medical insurance industry and even inspired folk-hero sentiment toward his killer. But Pennsylvania Gov. Josh Shapiro sharply refuted that perception after Mangione's arrest on Monday when a customer at a McDonald's restaurant in Pennsylvania spotted Mangione eating and noticed he resembled the shooting suspect in security-camera photos released by New York police. “In some dark corners, this killer is being hailed as a hero. Hear me on this, he is no hero,” Shapiro said. “The real hero in this story is the person who called 911 at McDonald’s this morning.” Mangione comes from a prominent Maryland family. His grandfather, Nick Mangione, who died in 2008, was a successful real estate developer. One of his best-known projects was Turf Valley Resort, a sprawling luxury retreat and conference center outside Baltimore that he purchased in 1978. The Mangione family also purchased Hayfields Country Club north of Baltimore in 1986. On Monday, Baltimore County police officers blocked off an entrance to the property, which public records link to Luigi Mangione’s parents. Reporters and photographers gathered outside the entrance. The father of 10 children, Nick Mangione prepared his five sons — including Luigi Mangione’s father, Louis Mangione — to help manage the family business, according to a 2003 Washington Post report. Nick Mangione had 37 grandchildren, including Luigi, according to the grandfather's obituary. Luigi Mangione’s grandparents donated to charities through the Mangione Family Foundation, according to a statement from Loyola University commemorating Nick Mangione’s wife’s death in 2023. They donated to various causes, including Catholic organizations, colleges and the arts. One of Luigi Mangione’s cousins is Republican Maryland state legislator Nino Mangione, a spokesman for the lawmaker’s office confirmed. “Our family is shocked and devastated by Luigi’s arrest,” Mangione’s family said in a statement posted on social media by Nino Mangione. “We offer our prayers to the family of Brian Thompson and we ask people to pray for all involved.” Mangione, who was valedictorian of his elite Maryland prep school, earned undergraduate and graduate degrees in computer science in 2020 from the University of Pennsylvania, a university spokesman told The Associated Press. He learned to code in high school and helped start a club at Penn for people interested in gaming and game design, according to a 2018 story in Penn Today, a campus publication. His social media posts suggest he belonged to the fraternity Phi Kappa Psi. They also show him taking part in a 2019 program at Stanford University, and in photos with family and friends at the Jersey Shore and in Hawaii, San Diego, Puerto Rico, and other destinations. The Gilman School, from which Mangione graduated in 2016, is one of Baltimore’s elite prep schools. The children of some of the city’s wealthiest and most prominent residents, including Orioles legend Cal Ripken Jr., have attended the school. Its alumni include sportswriter Frank Deford and former Arizona Gov. Fife Symington. In his valedictory speech, Luigi Mangione described his classmates’ “incredible courage to explore the unknown and try new things.” Mangione took a software programming internship after high school at Maryland-based video game studio Firaxis, where he fixed bugs on the hit strategy game Civilization 6, according to a LinkedIn profile. Firaxis' parent company, Take-Two Interactive, said it would not comment on former employees. He more recently worked at the car-buying website TrueCar, but has not worked there since 2023, the head of the Santa Monica, California-based company confirmed to the AP. From January to June 2022, Mangione lived at Surfbreak, a “co-living” space at the edge of touristy Waikiki in Honolulu. Like other residents of the shared penthouse catering to remote workers, Mangione underwent a background check, said Josiah Ryan, a spokesperson for owner and founder R.J. Martin. “Luigi was just widely considered to be a great guy. There were no complaints,” Ryan said. “There was no sign that might point to these alleged crimes they’re saying he committed.” At Surfbreak, Martin learned Mangione had severe back pain from childhood that interfered with many aspects of his life, including surfing, Ryan said. “He went surfing with R.J. once but it didn’t work out because of his back,” Ryan said, but noted that Mangione and Martin often went together to a rock-climbing gym. Mangione left Surfbreak to get surgery on the mainland, Ryan said, then later returned to Honolulu and rented an apartment. An image posted to a social media account linked to Mangione showed what appeared to be an X-ray of a metal rod and multiple screws inserted into someone's lower spine. Martin stopped hearing from Mangione six months to a year ago. An X account linked to Mangione includes recent posts about the negative impact of smartphones on children; healthy eating and exercise habits; psychological theories; and a quote from Indian philosopher Jiddu Krishnamurti about the dangers of becoming “well-adjusted to a profoundly sick society.” Mangione likely was motivated by his anger at what he called “parasitic” health insurance companies and a disdain for corporate greed, according to a law enforcement bulletin obtained by AP. He wrote that the U.S. has the most expensive healthcare system in the world and that the profits of major corporations continue to rise while “our life expectancy” does not, according to the bulletin, based on a review of the suspect’s handwritten notes and social media posts. He appeared to view the targeted killing of the UnitedHealthcare CEO as a symbolic takedown, asserting in his note that he is the “first to face it with such brutal honesty,” the bulletin said. Mangione called “Unabomber” Ted Kaczynski a “political revolutionary” and may have found inspiration from the man who carried out a series of bombings while railing against modern society and technology, the document said. Associated Press reporters Lea Skene in Baltimore; Jennifer Sinco Kelleher in Honolulu; Maryclaire Dale in Philadelphia; John Seewer in Toledo, Ohio; and Michael Kunzelman in Washington, D.C., contributed to this report.
Panaji (Goa) [India], November 22 (ANI): Director Nikkhil Advani talked about his series ‘Freedom at Midnight’, which is based on the events that took place around India’s independence and partition. In a conversation with ANI, he opened up on his research work and why he decided to make this web show. The reference for his project was “‘Freedom at Midnight’,” a book by Larry Collins and Dominique Lapierre about the events around the Indian independence movement and partition. He said it is a popular book and many books on history and other subjects are difficult to understand but it touched his heart. “When I was 16 years old, when I was 25 years old, whenever I picked up this book...and I have three copies of this book in my house.” Another book that he referred was brought by his friend, as he recalled at the International Film Festival of India (IFFI) in Goa. “There was one book that my friend bought for me that he got in a small village of England and there were notes of Lord Mountbatten... We also read other stuffs for the research on different events “ The series is a dramatized account of the tumultuous events surrounding India’s struggle for independence and the chaotic partition. The key figures in India’s independence movement, including Jawaharlal Nehru, Mahatma Gandhi, Sardar Vallabhbhai Patel, and Muhammad Ali Jinnah, are brought to life in vivid detail, setting the stage for the series’ exploration of this pivotal moment in history. The drama doesn’t shy away from the political complexities of the time, capturing the tensions between the founding fathers of India and the colonial rulers. He asserted that he wanted to show people the events and decisions that were being taken at the time of independence, ” I wanted to do that. I wanted to show, I wanted the audience to come to the same room where these people are taking very difficult decisions.” ‘Freedom at Midnight’ is produced by Emmay Entertainment (Monisha Advani and Madhu Bhojwani) in association with StudioNext. The series is helmed by Nikkhil Advani, who serves as both the showrunner and director. The writing team behind the series includes Abhinandan Gupta, Adwitiya Kareng Das, Gundeep Kaur, Divya Nidhi Sharma, Revanta Sarabhai, and Ethan Taylor. The series boasts an ensemble cast. Sidhant Gupta plays Jawaharlal Nehru, while Chirag Vohra takes on the role of Mahatma Gandhi. Rajendra Chawla stars as Sardar Vallabhbhai Patel, and Arif Zakaria portrays Muhammad Ali Jinnah. Other notable cast members include Ira Dubey as Fatima Jinnah, Malishka Mendonsa as Sarojini Naidu, and Rajesh Kumar as Liaquat Ali Khan. The show also features Luke McGibney as Lord Louis Mountbatten, Cordelia Bugeja as Lady Edwina Mountbatten, Alistair Finlay as Archibald Wavell, and Andrew Cullum as Clement Attlee, among other pivotal roles. ‘Freedom at Midnight’ is streaming on Sony LIV. (ANI) This report is auto-generated from ANI news service. ThePrint holds no responsibility for its content. var ytflag = 0;var myListener = function() {document.removeEventListener('mousemove', myListener, false);lazyloadmyframes();};document.addEventListener('mousemove', myListener, false);window.addEventListener('scroll', function() {if (ytflag == 0) {lazyloadmyframes();ytflag = 1;}});function lazyloadmyframes() {var ytv = document.getElementsByClassName("klazyiframe");for (var i = 0; i < ytv.length; i++) {ytv[i].src = ytv[i].getAttribute('data-src');}} Save my name, email, and website in this browser for the next time I comment. Δ document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() );
Dow Hits New Record HighTLSI stock touches 52-week low at $3.5 amid market challenges
NoneLeslies stock plunges to 52-week low at $2.24 amid market challenges(The Center Square) - California Gov. Gavin Newsom said if President-elect Donald Trump ends the $7,500 electric vehicle rebate program, he’ll get Californians to pay for new credits. However, the credits would not include Tesla, which is the most popular EV company and the only EV manufacturer in the state. This comes weeks after Newsom and his administration passed new refinery and carbon credit regulations that will add up to $1.15 per gallon of gasoline and require Californians with gasoline-powered cars to earn up to another $1,000 per year in pretax income to afford. “We will intervene if the Trump Administration eliminates the federal tax credit, doubling down on our commitment to clean air and green jobs in California,” said Newsom in a statement. Tesla CEO Elon Musk, whose rocket launches were recently blocked by a California regulatory board that cited his personal politics, shared his disapproval on his social media platform, X, after Newsom staff told Bloomberg that Tesla models would not qualify for California rebates. “Even though Tesla is the only company who manufactures their EVs in California,” said Musk. “This is insane.” Musk recently moved SpaceX and X out of California, citing a new law signed by Newsom banning parental notification for gender change requests from K-12 students. The credits would be paid for through California’s cap-and-trade program, which requires carbon emitters to purchase credits from the state — costs which are generally passed on to consumers in the form of more expensive gasoline, energy, and even concrete. Emitters buy a few billion dollars worth of credits from California each year, with the state’s $135 billion high speed rail project getting the lion’s share of the revenue. The California Resources Board — all but two of whose voting members are appointed by the governor — recently approved $105 billion in EV charging credits and $8 billion in hydrogen charging credits to be largely paid for by drivers of gas cars and diesel trucks. An investigation by The Center Square found the change was pushed by EV makers and the builders of EV charging systems. Buyers of EV chargers, who pay for the energy and own the charger, sign installation contracts that permanently give away their rights to government or other EV charging credits generated from fueling a vehicle with electrons instead of gasoline. These chargers are often bundled with the purchase of an EV, or covered entirely by utility or government rebates, meaning they are permanent, zero-or-low-cost revenue streams for the company collecting the credits. Get any of our free email newsletters — news headlines, sports, arts & entertainment, state legislature, CFD news, and more.
Longest-lived US president was always happy to speak his mindThe City of Pembroke says repair work at the Kinsmen Pool is in its final stages, and it could reopen early in the new year. The city closed the public pool at the start of January, describing the 51-year-old building as "at its end of life." Council voted to move forward with a $1.4-million repair plan , which the City of Pembroke said in a news release Monday was initially expected to be completed in September , but it has faced delays related to lighting and extensive damage to the tile on the pool deck. "The lighting repairs are done, which has allowed the contractors to start the repairs on the damaged tile. Unfortunately, the repairs couldn't be done simultaneously because of the installation and cure time requirements of tile," the release said. Once contracted work is complete, there would be additional work by the city's Parks and Recreation Department to prepare for opening. City staff said there is no confirmed date yet for when the pool will reopen. "A date for the pool's re-opening is not available currently as work is still underway, but it is expected to reopen in the early part of the New Year," the City of Pembroke said. To help pay for the expense, Pembroke called on surrounding municipalities and organizations to help cover costs. The City said Monday that the Township of Laurentian Valley has confirmed that it would contribute up to 30 per cent of the net cost to a maximum of $420,000, and that the Friends of the Regional Pool group has managed to raise $92,000 so far through fundraising efforts. "The ongoing renovations have been unexpected, but necessary to be ready for safe use of our pool facility," said Mayor Ron Gervais in the release. "We are excited to see the project continuing to move along and continue to ask for patience as we finalize the project." Pembroke City Council initially voted against the repair plan, suggesting instead the City explore building a brand new pool, at an estimated cost of $40 million, with a five to seven-year build time. Community members pushed back against that idea, and council later agreed to go ahead with repairs. The repair work has been ongoing since June. Ottawa Top Stories FREEZING RAIN WARNING | 1 to 3 mm of freezing rain possible in Ottawa-Gatineau tonight OC Transpo well below punctuality targets on 'less frequent' routes Cargo ship runs aground in St. Lawrence River near Morrisburg, Ont. OC Transpo hands out 1,900 fines to riders not paying fares in 2 months Katy Perry coming to Ottawa next summer Renovated pool in Pembroke, Ont. could reopen in early 2025 $10k worth of cannabis stolen from Renfrew, Ont. store MISSING | Ottawa police seek help locating missing 31-year-old man CTVNews.ca Top Stories 'It's just not fair': Retirees speak out on being excluded from federal rebate cheques Carol Sheaves of Moncton, N.B., says it's not fair that retirees like her won't get the government's newly proposed rebate cheques. Sheaves was among the seniors who expressed their frustrations to CTVNews.ca about not being eligible for the $250 government benefit. Warren Buffett gives away another US$1.1B, announces plans for distributing $147B fortune after death Investor Warren Buffett renewed his Thanksgiving tradition of giving by announcing plans Monday to hand more than US$1.1 billion of Berkshire Hathaway stock to four of his family's foundations, and he offered new details about who will be handing out the rest of his fortune after his death. Premiers seek 'urgent' meeting with Trudeau before Trump returns to White House Canada's premiers are asking Prime Minister Justin Trudeau to hold an urgent first ministers' meeting ahead of the return to office of president-elect Donald Trump. Deer spotted wearing high-visibility safety jacket in Northern B.C. Andrea Arnold is used to having to slow down to let deer cross the road in her Northern B.C. community. But this weekend she saw something that made her pull over and snap a photo. Canada Post says progress 'limited' at negotiating table as strike continues Canada Post says they have made 'limited progress' with the union at the negotiating table 11 days after the strike began. Los Angeles judge postpones hearing on release of Menendez brothers A Los Angeles County judge on Monday postponed a hearing over the possible release of Lyle and Erik Menendez after 35 years in prison for the shotgun murder of their parents, saying he wanted to hear from a new district attorney due to take office on Dec. 3. Canadian Army corporal fined for stolen valour at Remembrance Day ceremony A corporal in the Canadian Army has been fined $2,000 and given a severe reprimand for wearing service medals he didn't earn during a Remembrance Day ceremony in Alberta two years ago. Defence Minister Bill Blair 'ready to go faster' on spending timeline Defence Minister Bill Blair said Monday that he's ready to work with the incoming Donald Trump administration to speed up Canada's timeline to meet its NATO alliance spending targets. CEOs demand changes to Liberals' military spending plan The federal government risks jeopardizing the economy unless it meets its NATO military alliance spending obligations within the next five years, says the Business Council of Canada. Shopping Trends The Shopping Trends team is independent of the journalists at CTV News. We may earn a commission when you use our links to shop. Read about us. Editor's Picks 27 Of The Absolute Best Stocking Stuffers For Men 24 Of The Best Host And Hostess Gifts You Can Find Online Right Now 21 Of The Absolute Best Stocking Stuffers For Kids (And They're All From Amazon Canada) Home Our Guide To The Best Stand Mixers In Canada In 2024 (And Where To Get Them) Our Guide To The Best Nespresso Machines in Canada in 2024 (And Where to Get Them) Our Guide to the Best Jewellery Boxes You Can Find Online Right Now Gifts 19 Of The Best Tech Gifts Under $100 17 Gifts Your Husband Actually Wants 23 Gifts, Add-Ons, And Stocking Stuffers For Anyone Who Spends A Lot Of Time In Their Car Beauty 20 Anti-Aging Skincare Products That Reviewers Can’t Stop Talking About 12 Budget-Friendly Makeup Brushes And Tools Worth Adding To Your Kit If You Suffer From Dry Skin, You'll Want To Add At Least One Of These Hydrating Moisturizers To Your Cart Deals From Anthropologie To Adidas: Here Are The Best Early Black Friday Deals On Clothing And Accessories These Apple Products Are Majorly On Sale On Amazon Canada Right Now, So It Might Be Time To Upgrade Your Tech Black Friday Has Begun On Amazon Canada: Here Are The Best Deals Atlantic 'It's just not fair': Retirees speak out on being excluded from federal rebate cheques Carol Sheaves of Moncton, N.B., says it's not fair that retirees like her won't get the government's newly proposed rebate cheques. Sheaves was among the seniors who expressed their frustrations to CTVNews.ca about not being eligible for the $250 government benefit. Man charged with unsafe storage of a firearm in Tyson MacDonald homicide: RCMP A 61-year-old man is facing unsafe storage charges in connection with the homicide of 17-year-old Tyson MacDonald on P.E.I., last December. From cellphones to dentures: Inside Halifax Transit’s lost and found Every single item misplaced on a bus or ferry in the Halifax Regional Municipality ends up in a small office at the Halifax Transit Bridge Terminal in Dartmouth, N.S. Toronto Ontario government passes bill to limit bike lanes Ontario's Progressive Conservative government has passed a controversial law that will force municipalities to seek approval for installing new bike lanes on arterial roads and could see some existing bike lanes torn up. Toronto mother now facing murder charge in death of four-month old baby Toronto police say they have charged a mother with second-degree murder following the death of her infant, who was found with critical injuries in midtown Toronto last week. 'Embarrassing:' NHL team ditches bus and walks to Scotiabank Arena amid gridlock The Utah Hockey Club got the full Toronto experience Sunday night ahead of their first-ever matchup against the Maple Leafs—bumper-to-bumper traffic that forced the team to walk to the game. Montreal More people hurt in Quebec road accidents after fall time change, data shows New data from Quebec's auto insurance board shows that evening road accidents -- including those involving pedestrians -- rise sharply in the 30 days following the fall time change, when the sun sets earlier. Montreal mayor says Friday pro-Palestinian protests were taken over by 'professional vandals' Montreal Mayor Valérie Plante told journalists 'professional vandals' took over protests and smashed windows at the Palais des Congres. Teen girls engage in more risky behaviour than boys: Quebec study Fewer young people in Quebec secondary schools are drinking alcohol, consuming sugary drinks and eating junk food, but not all their habits are improving. More of them are also inactive, taking action to change their weight and not eating breakfast before going to school, according to a recent study. Northern Ontario Elliot Lake, Ont., woman charged with choking neighbour's dog An intoxicated woman in Elliot Lake has been charged with breaking into her neighbour's apartment and choking their dog. Winter weather advisory in effect for most of northeastern Ont. Environment Canada has issued a winter weather advisory for areas in and around Greater Sudbury, North Bay, Sault Ste. Marie and Timmins. Drug bust after a suspect pointed handgun at victim at northern Ont. gas station Three people have been charged with numerous drug and weapons offences following an incident at a gas station in Bruce Mines, Ont., on Nov. 21. Windsor 'Active investigation' underway in Windsor Windsor police are on the scene of what's being called an, "active investigation." "Expect a sustained police presence in the area," read a post on social media. Memorial put up on Walker Road after fatal crash A memorial is located on Walker Road to mark the site where a Windsor couple was killed after getting struck by a vehicle. Alleged impaired mom found asleep at the wheel with two kids in the backseat Windsor police arrested two motorists for impaired driving in separate incidents over the weekend, including a mom with two small children in the backseat. London 'It’s getting dangerous downtown': Rear entrance of London business sprayed with gunfire London police said that no-one was injured when the back entrance of a downtown cannabis shop was sprayed with gunfire early on Monday morning. 'I just knew something was up': London family recounts rushing to their burning home where pet perished A weekend house fire has left a family displaced and taken the life of a beloved pet. The blaze at 454 Alston Road broke out shortly after 12:30 p.m. Christmas tax break will be 'challenging' for small businesses, says gift shop owner Tom Fincher is all for a tax break for consumers but implementing the GST tax break announced by the federal government last week at his till will be easier said than done. Kitchener Waterloo reviews most collision-prone areas to improve safety The City of Waterloo is trying to make its roads safer by putting together a report on some of the locations with the most crashes in the past five years. Driver warned after police receive complaints about car decked out in Christmas lights in Waterloo Drivers are being reminded not to take the holiday spirit too far after police received complaints about a distracting vehicle in Waterloo. Kitchener, Ont. doctor officially claims second Guinness World Record A Kitchener, Ont. emergency room doctor has officially earned his second Guinness World Records title. Barrie 'James deceived us,' Slain Collingwood, Ont. woman's family speak ahead of husband's sentencing James Schwalm sat in the prisoner’s box Monday morning weeping as friends and family members told the court about the devastation he caused when he murdered his wife, Ashley Milne, two years ago inside their Collingwood, Ont. home. Novice driver charged with speeding 95km/h over limit on Hwy 11 accused of being impaired A Thornhill resident accused of driving at a high rate of speed along Highway 11 in Muskoka while impaired faces charges. Freezing rain, snow in the forecast for Muskoka A freezing rain warning is in effect for Muskoka, with slippery roads and power outages possible. Winnipeg Winnipeg police shoot, kill suspect after officer stabbed in the throat Manitoba’s police watchdog is investigating a deadly police shooting at Winnipeg's Unicity Shopping Centre Sunday evening. Mounties looking for missing car in connection with suspicious death Manitoba RCMP are looking for a missing car connected to an investigation into human remains discovered north of Winnipeg. $4.2M from feds to create Indigenous-led family care centre in Winnipeg A new Indigenous-led family care centre will be coming to Winnipeg, with more than $4.2 million for the project coming from the federal government. Calgary Alberta seeks to 'de-risk' oil, gas pipeline investments in wake of Trump victory Alberta Premier Danielle Smith says her government is looking for ways to encourage pipeline companies to boost capacity and increase Alberta's oil and gas export volumes to the U.S. $3.69M Calgary mansion with basketball court for sale in Aspen Woods If you've ever dreamed of having a home with a basketball court, now's your chance. Alberta aiming to create test site to support new drilling technologies Alberta’s government says it will invest up to $50 million to support the creation of a first-in-Canada drilling test site to support technology development in the oil, gas, geothermal and lithium industries. Edmonton 24 arsons in south Edmonton under police investigation The Edmonton Police Service now says it is investigating 24 suspicious fires in south Edmonton. Death of worker in Edmonton smokehouse leads to 26 charges against food processing company An Ontario-based food processing company is facing 26 charges under Alberta Occupational Health and Safety legislation in connection with the death of a worker at an Edmonton facility in 2023. The story of Alberta's rural long COVID program that never was As better diagnosis and symptom management emerged for people with long COVID, researchers in Alberta set to work creating a program that could remotely connect urban specialists and rural patients. Between development and clinical implementation, the project was shelved. Regina Sask. Party prioritizes affordability, civility with opposition in Throne Speech The Saskatchewan Party government said it will prioritize affordability in the coming months during its Throne Speech on Monday, that officially kicked off a short two-week sitting inside the legislature. Regina commits to clearing all 'high priority roads' of snow by Tuesday morning Following a second significant dump of snow in less than a week, the City of Regina says it plans to have all high priority roadways cleared by 7:00 a.m. Tuesday. Regina police release images of suspects following early morning armed robbery Regina police are looking for two people following an early morning armed robbery in the city's downtown on Monday. Saskatoon Sask. Party prioritizes affordability, civility with opposition in Throne Speech The Saskatchewan Party government said it will prioritize affordability in the coming months during its Throne Speech on Monday, that officially kicked off a short two-week sitting inside the legislature. Saskatoon's second big snowfall in a week won't trigger emergency response: City City crews and contractors are at it again — clearing roadways after another major snowfall. Two dead after crash on Saskatchewan Highway 4 Two people are dead following a two-vehicle crash on Highway 4 Friday evening. Vancouver Deer spotted wearing high-visibility safety jacket in Northern B.C. Andrea Arnold is used to having to slow down to let deer cross the road in her Northern B.C. community. But this weekend she saw something that made her pull over and snap a photo. Wild weather behind 11-cent surge in Vancouver gas prices, analyst says The intense storms that battered parts of B.C. and the United States last week are partly to blame for a significant surge in Vancouver gas prices, according to a petroleum analyst. Canadian border agents seize 246 kilos of cocaine in B.C. Canadian border officials in British Columbia have seized nearly a quarter-tonne of cocaine that was coming into the province in three separate smuggling incidents in recent weeks, according to the agency. Vancouver Island Canadian Army corporal fined for stolen valour at Remembrance Day ceremony A corporal in the Canadian Army has been fined $2,000 and given a severe reprimand for wearing service medals he didn't earn during a Remembrance Day ceremony in Alberta two years ago. Deer spotted wearing high-visibility safety jacket in Northern B.C. Andrea Arnold is used to having to slow down to let deer cross the road in her Northern B.C. community. But this weekend she saw something that made her pull over and snap a photo. Vancouver Whitecaps drop head coach Vanni Sartini Two weeks after the Vancouver Whitecaps’ playoff run ended in the first round, the team has fired head coach Vanni Sartini. Kelowna Man in hospital following targeted shooting in Kamloops Police are appealing for information on a targeted shooting that resulted in the hospitalization of a man in Kamloops. Police cleared of fault in fatal 2023 crash in B.C.'s Interior British Columbia's independent police watchdog has cleared officers of wrongdoing in a crash where three people were killed south of Kamloops in July of last year. B.C. woman sentenced for stealing $14K in funds raised for schoolkids A B.C. woman who stole more than $14,000 in volunteer-raised funds that were supposed to be spent on school supplies and programs – including hot meals for vulnerable kids – won't spend any time in jail. Stay ConnectedRevolutionary bioengineering research may transform type 1 diabetes care, pave way for tackling cancer and autoimmune disease November 25, 2024 Medical University of South Carolina Researchers recently collaborated on a novel, highly specific strategy to treat type 1 diabetes (T1D) using a tagged beta cell transplant in tandem with localized immune protection provided by specialized immune cells also tagged with a complementary but inert targeting molecule. Facebook Twitter Pinterest LinkedIN Email Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options for anyone who needs a transplant. This revolutionary field still faces many challenges, including the nontrivial task of convincing stem cells to differentiate into desired cell types for treatment. And even if the correct cells or tissues are created and can function successfully in the body, immune rejection presents a formidable barrier to their use. To overcome this obstacle, regenerative medicine treatments in use today require systemic immunosuppression, leaving patients vulnerable to environmental hazards like viruses, bacteria and cancer cells. In a novel approach to tackle these obstacles, researchers at the Medical University of South Carolina and the University of Florida recently collaborated on a novel, highly specific strategy to treat type 1 diabetes (T1D) using a tagged beta cell transplant in tandem with localized immune protection provided by specialized immune cells also tagged with a complementary but inert targeting molecule. According to Leonardo Ferreira, Ph.D., a researcher at MUSC Hollings Cancer Center and one of the principal investigators on the study, marrying stem cell engineering and regulatory T cell (Treg) engineering allowed the first step toward a readily available, off-the-shelf solution to treating T1D. In their recent study published in the journal Cell Reports , the researchers described a unique collaboration that leveraged the beta cell engineering expertise of the lab of Holger Russ, an associate professor of pharmacology and therapeutics at the University of Florida, combined with the delicate surgical expertise and chimeric antigen receptor (CAR) T cell expertise available at Hollings. For T1D patients, the trouble begins with an immune system self-attack on pancreatic beta cells, the cells that produce the hormone insulin to regulate blood sugar levels. Without a reliable way to self-regulate blood glucose levels, patients are forced to live with a high-maintenance regimen of glucose monitoring and insulin management to maintain health and avoid dangerous complications like neuropathy, amputation and blindness. For now, some patients with poorly controlled T1D may consider islet cell transplantation using beta cells from a donor. Beta cells are isolated from a donor pancreas, purified and delivered to the patient's liver, where they can take up residence and begin secreting insulin. However, this option requires patients to undergo immunosuppression for the rest of their lives to keep the body from rejecting the foreign beta cells. It also requires the availability of donor cells, which might require long waits or may not happen at all. To focus on an alternative solution, the researchers used an engineering strategy with tagged beta cells generated from stem cells. And to induce localized immune protection, the researchers chose to use Tregs, a type of immune cell that monitors and controls the immune response. "Most of the cells of the immune system are focused on killing invasive elements," Ferreira said. "But Tregs are the generals of the immune system. They make sure that nothing goes overboard, and they train the immune system on how to respond in the future." The researchers used a mouse model to test their strategy. By transplanting beta cells that were engineered from stem cells and included a nonreactive tag -- an inactivated version of epidermal growth factor receptor -- into the kidney capsules of immunodeficient mice, they showed that the cells were incorporated and began to manufacture functional insulin. In the next phase of testing, the mice were exposed to an aggressive type of immune cell to check on the viability of the transplanted beta cells in the face of a simulated immune response. As expected, all of the beta cells were killed by the immune response, the same thing that happens in people with T1D. To avoid the killing response in the next phase, the researchers added specialized Tregs along with the immune challenge. These cells were tagged with CAR technology using a receptor that specifically recognized the inert EGFR tag present on the transplanted beta cells. With this added step, the researchers observed the immune protection they hoped for, as they observed the transplanted beta cells remaining safe, sound and functional in their new home. Ferreira was delighted with the results and energized to take the next steps. "With this approach," he said, "we made both the lock and the key for creating immune tolerance." Now that Ferreira and colleagues have shown the feasibility of their approach to T1D treatment, they plan to continue their research efforts, including building a whole library of locks and keys -- differentiated stem cells and tagged protective Tregs -- for multiple purposes, such as targeting certain cancers, lupus and other autoimmune diseases. A few questions remain, such as the specific ligand that should be used for human transplantation and the longevity of Treg-mediated immune protection. The ligand or tag must be inert and have no negative impact on the function of the cells or create any reaction that could cause side effects. And it is still unknown if one Treg treatment will be effective or might need to be repeated at intervals that have yet to be established. Because Tregs can educate immune cells to maintain immune tolerance, it is possible that one treatment will be adequate, but further research is needed to understand the long-term effects. Answering these questions and confirming the validity of the approach in humans may soon transform T1D from a chronic, high-maintenance disease with many complications to one that can be managed much more easily. Story Source: Materials provided by Medical University of South Carolina . Original written by Shawn Oberrath. Note: Content may be edited for style and length. Journal Reference : Cite This Page :Donald Trump Jr emerges as a political force of his own as he helps his father launch a second term
Rogers Communications Inc. Cl B stock rises Friday, outperforms market
Denver Mayor Mike Johnston sets off firestorm with vows to resist Donald Trump’s mass deportation plansDallas Cowboys star guard Zack Martin is doubtful for Sunday's game against the Washington Commanders due to ankle and shoulder injuries. Martin didn't practice at all this week. He also physically struggled during Monday night's loss to the Houston Texas. Martin, who turned 34 on Wednesday, has started all 162 games played in 11 seasons with the Cowboys. He's a nine-time Pro Bowl selection and a seven-time first-team All-Pro. Tight end Jake Ferguson (concussion) and safety Markquese Bell (shoulder) have been ruled out. Neither player practiced this week after being hurt against the Texans. Cornerback DaRon Bland (foot) practiced in full this week and will make his season debut. He was injured in August. Star wideout CeeDee Lamb (back/foot) was a full practice participant on Friday and is good to go. Cornerback Trevon Diggs (groin/knee) and receiver Brandin Cooks (knee) are among six players listed as questionable. The others are offensive tackle Chuma Edoga (toe), guard Tyler Smith (ankle/knee), defensive end Marshawn Kneeland (knee) and linebacker Nick Vigil (foot). --Field Level Media
Back in April, Billboard magazine, the music industry’s recordkeeper for chart success, took the chance to try to predict what would be the song of the summer. At the time the publication considered Beyoncé’s “Texas Hold ’Em” and Ariana Grande’s “We Can’t Be Friends” to be front-runners, as well as “Like That,” the collaboration by rappers Future, Metro Boomin and Kendrick Lamar. Two weeks after Billboard asked what would be the song of 2024’s summer, Drake released “Push Ups.” The track insulted a number of people in the rap industry, but Drake took particular aim at Lamar, going so far as to mock his height and shoe size. Drake came at Lamar directly the following week with “Taylor Made Freestyle.” And on the last day of April, Lamar responded with the six-minute dissertation “Euphoria.” Eventually Billboard selected Post Malone’s “I Had Some Help” featuring Morgan Wallen as the “song of the summer.” Lamar’s chart topper “Not Like Us” — the fourth track in his back and forth with Drake — was somehow ranked third. I was a little shocked. To be honest, I thought the “song of summer” conversation was over in June after Lamar performed “Not Like Us” five times at his Pop Out concert at the Forum. Two Americas, I guess. Then again, “Not Like Us” is not a song, it’s a revelation as Lamar would say. A rather prescient one, considering how much racial tension and identity politics shaped the general election, particularly after Vice President Kamala Harris became the nominee. On “Like That” and “Euphoria,” Lamar threw haymakers at Drake. However, by the time we heard “Us,” Lamar was simply using Drake as a symbol to provoke a larger conversation about authenticity, accountability and manhood. Through that lens, including “Us” on a best-of-summer list is akin to referring to the locs on my head as a hairstyle — technically true, yet culturally tone-deaf. “Let me tell you what that record did do. It united the West,” Snoop Dogg said recently on the podcast “The Champs,” adding it made “everybody out here start looking at each other like how much love we got for each other ... so we should speak on that.” Absolutely. We certainly don’t have a problem talking about conflicts in hip-hop — whether a beef between two stars or a clash between Bloods and Crips. So why can’t we acknowledge the love? While other forms of music are routinely acknowledged for their healing power, the vulnerability embedded in the lyrics of hip-hop is often overlooked. And because of that, the humanity of the artist rapping those lyrics is easily overlooked. Lamar’s seven Grammy nominations this year, the Super Bowl gig lined up for next year and the streaming records are all outstanding. And none of that would have been possible without the social commentary that accompanies the music. This includes “GNX,” the surprise album Lamar released Friday. While he does continue to hammer away at Drake personally, the power of Lamar was always his ability to make a single story about an individual feel like an analogy about all of us. Where “Not Like Us” left off, “TV Off” and “Man at the Garden” picked up in terms of production value and searing observations. It’s funny to think that back in April, Lamar was somewhere minding his own business before Drake came for his crown — and missed. Since then, the culture has gone back and forth between headlines about something outlandish from the election and social media going crazy about another Kendrick Lamar surprise. Song of the summer? Record of the year? Those monikers couldn’t begin to encapsulate just how brilliant and bright Lamar has been in a year full of dark moments. Think of it this way: In 2012, LeBron James won the regular season MVP, an NBA title, Finals MVP and Olympic gold in London. Only one other player had accomplished all of that in a single year — Michael Jordan. That’s when the debate over who is better began in earnest. After cementing his legacy with a historic summer, James started the following season wearing a pair of gold gym shoes in honor of his Olympic achievement and officially announcing his arrival among the game’s greatest. As life would have it, the week before that game, Lamar announced his arrival among the greats as well, dropping “Good Kid, m.A.A.d City.” And like James he’s been breaking records ever since. However unlike for James, the debate over the greatest in Lamar’s game is over. @LZGranderson
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